Beta-lactamase & media plates
EUCODIS Bioscience manufactures and delivers “LacBuster™”, EUCODIS Bioscience's pure and high-performing beta-lactamases. LacBuster™ has been optimized for sterility testing and environmental monitoring in the manufacture and dosage formulation of beta-lactam antibiotics and for specific diagnostic purposes.
LacBuster™-L is a novel sterile ready-to-use solution. Due to its high performance LacBusterTM-L is especially well suited for the direct inoculation method and membrane filtration tests according to US Pharmacopeia (USP <71>) and EP. It can be directly implemented into existing standard operating procedures.
LacBuster™-S is a novel beta-lactamase formulation with a broad substrate range against beta-lactam antibiotics including all clinically relevant carbapenems, cephalosporins up to 5th generation and penicillins. LacBuster™ addresses the needs of leading antibiotics manufacturers and laboratories interested in sterility testing of biological specimens and shows a significantly higher efficacy than other products currently in the market.
Penase is a penicillinase with a specific substrate range solely against all relevant penicillins. Penase is available as a freeze-dried powder.
EUCODIS beta-lactamases offer:
- Broad substrate range
- GMP-compliant formulation (LacBuster-LTM)
- Long stability >1 year
Sterility Tests
| Product | Catalogue | Formulation | Sales Unit | Enzymatic Activity (IU/VIAL) | |
|---|---|---|---|---|---|
|
|
|
| Beta-Lactamase I | Beta-Lactamase II |
| LacBuster-L | EB008.1 | sterile liquid (10 ml) GMP | 10 | 2 500 | 1 000 |
| LacBuster-S | EB006.1 | sterile freeze-dried powder gamma irradiated | 10 | 500 | 50 |
| LacBuster-S | EB006.2 | sterile freeze-dried powder gamma irradiated | 1 | 20 000 | 2 000 |
| LacBuster-S | EB006.4 | freeze-dried powder non-irradiated | 1 | 50 000 | 5 000 |
| Penase | EB002.1 | freeze-dried powder | 1 | 3 300 | - |
All enzymes are also available in bulk quantities; please inquire at our sales team.
RELATED DOWNLOADS
LacBusterTM brochure
An overview of available formulations and product highlights >
Find out more
For price inquiries, please contact our sales team under
sales(at)eucodis.com >
LacBuster™ agar plates for environmental monitoring
EUCODIS Bioscience provides a general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. The media plates are suitable for the cultivation of a wide variety of microorganisms in environmental monitoring within the pharmaceutical industry. We offer contact and settle plates for high performance monitoring of your isolators and clean rooms during beta-lactam manufacture.
Why use LacBuster™ media plates?
- High enzymatic activity of 1 000 IU/L cephalosporinase and 10 000 IU/L penase
- Suitable for all commonly used disinfectants
- H2O2-impermeable triple-sleeve packaging
- Gamma-irradiated (20 – 35 kGy)
- Long shelf life: 7 months
- Convenient storage at room temperature
Environmental Monitoring
| Product | Formulation | Sales Unit | Enzymatic Activity (IU/L) | |
|---|---|---|---|---|
|
|
| Beta-Lactamase I | Beta-Lactamase II |
| LacBuster - settle plates | agar plates gamma irradiated | 10 | 10 000 | 1 000 |
| LacBuster - contact plates | agar plates gamma irradiated | 10 | 10 000 | 1 000 |
| LacBuster-S | for production of own agar plates | bulk | ||
All enzymes are also available in bulk quantities; please inquire at our sales team.
