EUCODIS Bioscience offers a collection of more than 50 unique lipases of microbial origin, carefully selected and engineered for applications in the pharmaceutical, cosmetic and fine chemical industry. Our lipases cover a broad range of substrates and are suitable for hydrolysis in aqueous solutions and esterifications in organic solvents.
25 lyophilized enzymes are available as standard screening kit (mg to kg) enabling rapid selection for your application. All enzymes can also be bought individually. Furthermore, we offer more than 30 additional lipases suitable for your substrate. Upon requests, bulk quantities or higher purity lipase preparations can be supplied.
EUCODIS Bioscience provides immobilized lipases suitable for organic solvents and higher temperature ranges. We offer Lipase immo Kit, a screening kit of 6 different immobilized lipases and tailor-made immobilized CalBs, customized for your application. Continuous bioreactors are available on request.
In addition to the lipase portfolio, EUCODIS Bioscience offers a range of suicide inhibitor substrates for lipases. The inhibitor substrates are designed for active site titration experiments and, e.g. can be used for the quantitative determination of active lipases and esterases in complex protein mixtures. They are ideally suited for quality control of hydrolytic enzymes like lipases and esterases, and are used for these applications in-house.
These phosphonate based molecules are available with either chromogenic (p-nitrophenyl derivatives) or fluorogenic (4-methyl-umbelliferyl derivative) groups for sensitive detection of hydrolytic activity of lipases and esterases. We also offer synthesis of customized lipase suicide inhibitors on demand.
Use: Chromogenic standard substrate (405 nm) for the determination of active sites in lipases.
Use: Chromogenic substrate (405 nm) for the determination of active sites in lipases preferring long chain leaving groups.
Use: Chromogenic substrate (405 nm) for the determination of active sites in lipases preferring hydrophobic leaving groups.
Use: Fluorogenic standard substrate (λex: 363 nm λem 465 nm) for the determination of active sites in lipases.